Bison Meatloaf with Green Chiles and Bacon

This hearty meatloaf combines rich bison with smoky bacon and a spicy kick from green chiles, making it a flavorful twist on a classic favorite. It’s perfect for a cozy dinner that’s both comforting and exciting.

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TIME1 hr 55 min

SERVINGS4

RATING4.8 / 5

Bison Meatloaf with Green Chiles and Bacon

COOKBOOK / 2851

01 / WHAT YOU NEED

Ingredients

Adjust servings4

1 ½ pounds ground bison 1 cup milk ½ cup Italian seasoned bread crumbs ½ cup chopped green chile peppers ½ cup bacon bits 1 large egg, beaten 1 ½ teaspoons liquid smoke flavoring 1 teaspoon onion powder ½ teaspoon dry mustard ¼ teaspoon garlic powder ¼ teaspoon ground sage ¾ cup barbeque sauce, or more to taste

02 / HOW TO MAKE IT

Let's cook.

01

Prepare and Bake Meatloaf

Start by heating your oven to 350°F (175°C). In a large bowl, combine the ground bison with milk, bread crumbs, chopped green chiles, bacon bits, egg, liquid smoke, onion powder, dry mustard, garlic powder, and ground sage. Use your hands to mix everything together well. Press the mixture evenly into a 9x5-inch loaf pan. Spread a generous layer of barbecue sauce over the top. Pop it in the oven and bake until the meatloaf is cooked through and no longer pink in the center, which should take about 1 hour and 45 minutes. Let it rest for a few minutes before slicing and serving.

03 / EXTRA DETAILS

Good to know.

Cook's tip

- Use a meat thermometer to ensure the meatloaf is cooked through without drying out.
- Let the meatloaf rest for 10 minutes after baking to help it hold together when slicing.
- If you like extra spice, add a pinch of cayenne pepper or diced jalapeños to the mix.

Why you’ll love it

This dish combines rich, hearty flavors with a smoky kick from the bacon and green chiles. It’s a great way to enjoy bison, which is leaner and more flavorful than traditional beef. The mix of ingredients keeps the meatloaf moist and satisfying.

Serving ideas

Serve this with creamy mashed potatoes or roasted vegetables to balance the smoky and spicy flavors. A fresh green salad or cornbread also pairs well to round out the meal.

Storage & leftovers

Store leftovers in an airtight container in the refrigerator for up to 3 days. You can also freeze slices wrapped tightly in plastic wrap and foil for up to 2 months. Reheat gently in the oven or microwave to keep the texture tender.